Diagnosed With RA, Prescribed Methotrexate And Prednisone. Another Advised HCQS. Which Therapy To Start?
Methotrexate is Preferable to HCQS.
Hi, thanks for writing to XXXXXXX
As per your description of Lab reports, you have high levels of disease activity and you need a swift response.
As both the medications tend to produce systemic adverse reactions if taken over a prolonged period of time, neither of them are absolutely safe.
Methotrexate is said to be the fastest acting DMARD (disease modifying antirheumatic drug) and its therapeutic effect can be seen within a month. Folic acid supplementation is a must along with methotrexate to counter its common side effects. Whereas HCQS needs to be taken for atleast 8 weeks before any clinical response can be appreciated.
So, I personally prefer Methotrexate to all my patients.
Hope I have justified your query. I welcome any clarification.