Suggest ways to wean off Sinemet

Posted on Mon, 29 May 2017 in Medicines and Side Effects
Question: What is the protocol for withdrawing from Sinemet? I have already reduced dosage to 1/2 dose 3 times per day.

I do not have Parkinson's Disease.
Answered by Dr. Ivo Ditah 52 minutes later
Brief Answer:
Can you please stat eteh exact mg you are taking daily?

Detailed Answer:
Hi and thanks so much for this query.

To be of most help, I will need to get a few more details from you.

1. For how long have you been on this drug?
2. What was the highest dose you ever used in mg?
3. What is the current dose in mg?
4. If you don't have Parkinson, why was this drug prescribed to you?
5. For how long have you been on this 1/2dose?

All these details are required to provide a personalised and helpful response to you. I hope to hear from you at your earliest convenience.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Follow up: Dr. Ivo Ditah 9 minutes later
I have been on Sinemet for 45 days.

Highest dose was 25/100 three times per day.

Currently doing 1/2 dose three times per day.

I have Secondary Progressive Multiple Sclerosis and I was "freezing" and taking many small steps to begin walking. DR. called it a "Parkinsonism" and prescribed Sinemet.

I have been on 1/2 dose for 1 week.

Answered by Dr. Ivo Ditah 3 hours later
Brief Answer:
Thanks and see below!

Detailed Answer:

Thanks for these details. I will suggest the following plan.

1. Step down the frequency to same dosage twice daily for one week.
2. Then same dosage once daily for another week
3. Same dosage every other day for one week.
4. Then stop it all together.

I wish you well and always available for further exchanges.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Answered by
Dr. Ivo Ditah

Internal Medicine Specialist

Practicing since :2002

Answered : 3922 Questions


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