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Suggest Treatment For Recurrent Blisters When Diagnosed With Bullous Pemphigoid
Question: my Husband has had bullous pemphioid since 6 XXXXXXX 2015 We have been all over northwest Arkansas. been treated with high levels of predisone and antibotics. We think it is going to clear up and then it is back again all over. some blisters are as big as a soft ball. He has never been totally free of the blister. he is getting weaker by the day. at night he has some kind of seziures. We are at our witys end. can you give us some kind of hint.
Brief Answer:
topical corticosteroids are beleived to be more efficacious
Detailed Answer:
hi,
Scientifically, topical corticosteroids are known to be better than treating patients with systemic corticosteroids.
Topical agents like clobetasol0.05% can be applied on all the lesions and the dose can be gradually decreased as the patient achieves remission.
However if due to certain problems topical agents cannot be used, and oral corticosteroids are being used, there is indication for starting immunosuppressive agents which are known to be steroid sparing like Azathioprine, Mycophenolate mofetil, or Methotrexate.
These drugs take time to take action ,how ever help in bringing down the dose of steroid, and bringing the disease into remission.
In certain cases not responsive to the above regimens, and completely refractory, there are biologic drugs like rituximab and iv immunoglobulin.
You can discuss these options with the treating doctor.
Regards
topical corticosteroids are beleived to be more efficacious
Detailed Answer:
hi,
Scientifically, topical corticosteroids are known to be better than treating patients with systemic corticosteroids.
Topical agents like clobetasol0.05% can be applied on all the lesions and the dose can be gradually decreased as the patient achieves remission.
However if due to certain problems topical agents cannot be used, and oral corticosteroids are being used, there is indication for starting immunosuppressive agents which are known to be steroid sparing like Azathioprine, Mycophenolate mofetil, or Methotrexate.
These drugs take time to take action ,how ever help in bringing down the dose of steroid, and bringing the disease into remission.
In certain cases not responsive to the above regimens, and completely refractory, there are biologic drugs like rituximab and iv immunoglobulin.
You can discuss these options with the treating doctor.
Regards
Above answer was peer-reviewed by :
Dr. Prasad
we have used the topical creams. You said nothing about Mayo. What happends if you can't control this
Brief Answer:
mayo has some of the best doctors.
Detailed Answer:
mayo has some of the best doctors.
you can consult there.
The comprehensive treatment needs to be face to face with the doctor.
mayo has some of the best doctors.
Detailed Answer:
mayo has some of the best doctors.
you can consult there.
The comprehensive treatment needs to be face to face with the doctor.
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Above answer was peer-reviewed by :
Dr. Raju A.T
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