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Is Switching From Lexapro To Paxil Safe?

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Posted on Wed, 18 Jan 2017
Question: I have been on lexapro for eight years. How hard will it be to change over to paxil?
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Answered by Dr. Seikhoo Bishnoi (26 minutes later)
Brief Answer:
It would not be much difficult

Detailed Answer:
Hi thanks for the query

Lexapro and Paxil both are SSRI drugs and it would not be very difficult to switch from Lexapro to Paxil. But since these are two different molecules so abrupt stoppage of Lexapro and starting Paxil is not advised. Cross tapering the drugs over 4 weeks would cause smooth transition.

You can reduce Lexapro to 10 and start controlled release 12.5 mg Paxil. In about 4 weeks Lexapro can be stopped completely and Paxil can be increased to 20 to 25 mg. This is what I advise my patients in my clinic. You may suffer slight restlessness, dizziness for a couple of days. Please discuss with your doctor before making any change in your prescription.

Thanks and Take care
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Veerisetty Shyamkumar
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Answered by
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Dr. Seikhoo Bishnoi

Psychiatrist

Practicing since :2007

Answered : 5193 Questions

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Is Switching From Lexapro To Paxil Safe?

Brief Answer: It would not be much difficult Detailed Answer: Hi thanks for the query Lexapro and Paxil both are SSRI drugs and it would not be very difficult to switch from Lexapro to Paxil. But since these are two different molecules so abrupt stoppage of Lexapro and starting Paxil is not advised. Cross tapering the drugs over 4 weeks would cause smooth transition. You can reduce Lexapro to 10 and start controlled release 12.5 mg Paxil. In about 4 weeks Lexapro can be stopped completely and Paxil can be increased to 20 to 25 mg. This is what I advise my patients in my clinic. You may suffer slight restlessness, dizziness for a couple of days. Please discuss with your doctor before making any change in your prescription. Thanks and Take care