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I Am 71 Years Old. An Orthpedic Doctor Recently Prescribed Celebrex 200mg Once Daily. My Questions Are: 1. Any Contraindications With These Medicines? 2. Any Particular Symptoms I Should Be Looking For In This Mixture Of Meds? Celebrex Can Cause Heart Attack And Stroke. Should This Cause Me Worry And To Stop Taking Celebrex?

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Posted on Thu, 19 Jan 2023
Question: I am 71 years old.
An orthpedic doctor recently prescribed Celebrex 200mg once daily which I started taking two weeks ago.
I%E2%80%99m already taking daily: Tylenol, Benecar hct , duloxetine, metformin, neurontin, uroxatral, propranolol, tizanadine, Azelastine (nose spray), Flutocasone Propionate (nose spray) and occasionally Stendra.
The reason for the Celebrex is that Mobic, meloxicam and dyclofenac sodium caused severe constipation and taking Linzess for the constipation resulted in diarrhea.
For the first two weeks with Celebrex, no constipation issues and no need to take Linzess any longer.
My questions are:
1. Any contraindications with these medicines?
2. Any particular symptoms I should be looking for in this mixture of meds?
3. I%E2%80%99ve read that Celebrex can cause heart attack and stroke. Should this cause me worry and to stop taking Celebrex?

doctor
Answered by Dr. Olgeta Xhufka (3 hours later)
Brief Answer:
Celecoxib interactions with other drugs.

Detailed Answer:
Hello,
I reviewed your query and here is my advice.

1. It is contraindicated if you allergic to sulfonamides ,are planning to have or recently have had heart surgery,have an active stomach or intestinal ulcer, have bleeding in brain,asthma, hives, or allergic-type reactions after taking aspirine or other NSAIDS
2. Look if your blood pressure values increase
Cekebrex lowers the effects of benecar.
It doesn't interact with tylenol , metformine and neurontine.
Lowers effects of duloxetine. Increase effect of propranolol.
Doesn't interact with tisanide and fluticasone spry.
Doesn't interact with uroxetral and stendra.
Talk to your doctor for possible adjusting dose of them.
3. It has risk of heart attack or stroke but your doctor has evaluated the situation and risks are so small and benefits overcome them. Don't have to worry.

Hope I have answered the question.
Let me know if I can assist you further.
Thanks
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Olgeta Xhufka

General & Family Physician

Practicing since :2011

Answered : 10166 Questions

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I Am 71 Years Old. An Orthpedic Doctor Recently Prescribed Celebrex 200mg Once Daily. My Questions Are: 1. Any Contraindications With These Medicines? 2. Any Particular Symptoms I Should Be Looking For In This Mixture Of Meds? Celebrex Can Cause Heart Attack And Stroke. Should This Cause Me Worry And To Stop Taking Celebrex?

Brief Answer: Celecoxib interactions with other drugs. Detailed Answer: Hello, I reviewed your query and here is my advice. 1. It is contraindicated if you allergic to sulfonamides ,are planning to have or recently have had heart surgery,have an active stomach or intestinal ulcer, have bleeding in brain,asthma, hives, or allergic-type reactions after taking aspirine or other NSAIDS 2. Look if your blood pressure values increase Cekebrex lowers the effects of benecar. It doesn't interact with tylenol , metformine and neurontine. Lowers effects of duloxetine. Increase effect of propranolol. Doesn't interact with tisanide and fluticasone spry. Doesn't interact with uroxetral and stendra. Talk to your doctor for possible adjusting dose of them. 3. It has risk of heart attack or stroke but your doctor has evaluated the situation and risks are so small and benefits overcome them. Don't have to worry. Hope I have answered the question. Let me know if I can assist you further. Thanks