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How Long Do Side Effects Of Sertindole Last?

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Posted on Thu, 3 Nov 2016
Question: Dear Dr. Sheppe,
I would like to know how long it takes to side effects of Serlect (sertindole) to go away, since i feel them strongly from 12 mg to 16 mg. Thanks beforehand, XXXXXXX
doctor
Answered by Dr. Alexander H. Sheppe (1 hour later)
Brief Answer:
Private Consultation

Detailed Answer:
Hello XXXXXXX and thanks so much for reaching out to me directly.

It should take no more than 14 days for the side effects you are experiencing to go away. It can take this long for anticholinergic and antihistaminic side effects to potential and develop tolerance in the body. If you are still experiencing side effects after 14 days, reach out to me and we can reassess, perhaps cut the dose increase in half (from 12mg to 14mg instead of from 12mg to 16mg) to go a bit slower.

Dr. Sheppe
Above answer was peer-reviewed by : Dr. Raju A.T
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Follow up: Dr. Alexander H. Sheppe (2 hours later)
Dear Dr. Sheppe,
Thanks for your answer. I just would like finally to know if Abilify can do a similar effect to Serlect in dopaminergic receptors with less side effects,
Thanks, XXXXXXX
doctor
Answered by Dr. Alexander H. Sheppe (2 days later)
Brief Answer:
Private Followup

Detailed Answer:
Abilify works a bit differently in that it both activates and blocks dopamine receptors. This may not work well in your case, because we know that activation of dopamine receptors worsens your symptoms. Although Abilify would likely have fewer side effects than Serlect, I do not think this would be a good medication for you at this time.

Dr. Sheppe
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Veerisetty Shyamkumar
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Answered by
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Dr. Alexander H. Sheppe

Psychiatrist

Practicing since :2014

Answered : 2236 Questions

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How Long Do Side Effects Of Sertindole Last?

Brief Answer: Private Consultation Detailed Answer: Hello XXXXXXX and thanks so much for reaching out to me directly. It should take no more than 14 days for the side effects you are experiencing to go away. It can take this long for anticholinergic and antihistaminic side effects to potential and develop tolerance in the body. If you are still experiencing side effects after 14 days, reach out to me and we can reassess, perhaps cut the dose increase in half (from 12mg to 14mg instead of from 12mg to 16mg) to go a bit slower. Dr. Sheppe