Does Lomotil interact with Xanax?

Posted on Tue, 9 Jun 2015 in Digestion and Bowels
Question: I currently take Lomotil (generic form) for occasional IBS type symptoms (particularly when I'm traveling, as I need to this weekend). The Lomotil sometimes helps me manage the stress of traveling (without accidental defecation) to the airport, checking in, long lines of security, etc.
My personal physician recommended a .25 Xanax to "help me" not have so much anxiety about the entire process (I've had numerous "accidents" and had to change clothes in the airport).
Can I anticipate any adverse interaction between Xanax and Lomotil? I've never taken Xanax before and I'm a little nervous about the effect. Thanks so much!
Answered by Dr. Kathy Robinson 3 hours later
Brief Answer:

Detailed Answer:
Hello and thank you for your question.
Usually I do not recommend xanax but this may actually be a situation where an occasional low dose xanax would be helpful. A 0.25 mg xanax is very low dose. Both xanax and lomotil can both cause sedation so there would be a chance of increased sedation from the combination but at that low dose of xanax I think it would be negligible.
Most doctors are very cautious about xanax because it is addictive and often abused. It does not work well for long term anxiety because of its short half life (doesn't stay around the body that long) however in your situation it may be very helpful to you.
I suggest that you try the combination at home some time before you try it on a trip or other outing. Then you will know if it is going to cause you to be too sedated. I doubt that it will but you at least will know what effects it will have if you try it at home before you really need it for an outing.
Good luck and I hope it is helpful to you.
K. Robinson
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Answered by
Dr. Kathy Robinson

General & Family Physician

Practicing since :1989

Answered : 3478 Questions


The User accepted the expert's answer

Share on
Question is related to
Diseases and Conditions ,   ,  

Recent questions on  Stress

doctor1 MD

i am 29 yrs old male unmaaried and mech engineer. i feel weak erection and often in stress and anxiety. due to that i found some disorders a my...

doctor1 MD

I have been experiencing severe upper back, rib and chest (side and frontal) pain, on both sides when I run. I had an ECG and Stress Test 2 weeks...

doctor1 MD

After a tremendous amount of stress all at once. 3 weeks into all this I started to experience upper back and neck stiffness and pain. Now 4 months...

doctor1 MD

I would like to know what ailment rebermac drug is indicated for. what is arthenesia a condition that i m being treated?. I have a long history of...

doctor1 MD

Hi Doctor, I want to improve my brain performance, so visited Ayurvedic doctor to take the swarna bhasma,i am little obese and having snoring...

doctor1 MD

hi i m facing sleep disturbance since last 8 years i feel too much pressure over and behing myleft ears may be it leads to stress and breaks my...

doctor1 MD

I have low body temperature, and am concerned that my thyroid may be not working optimally. My TSH is 4.13. If I reduce the stress in my life, will...

Get personalised answers from verified doctor in minutes across 80+ specialties

188 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction