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Dr. Andrew Rynne
Dr. Andrew Rynne

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Exp 50 years

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Does Aspirin interact with Ketorolac and Ibuprofen?

Answered by
Dr. Muhammad Sareer Khalil

General & Family Physician

Practicing since :2012

Answered : 2919 Questions

Posted on Sat, 10 Sep 2016 in Medicines and Side Effects
Question: I have already been through this but I will try again . Is there a over the counter pain med I can take with Ketorolac ? My doctor injected me with this drug yesterday evening . Sent me home and told me to take 2-3 Aleve 200mg up to 3xa day (24) hours . Makes my stomach hurt so after taking 4 total in 24 hours I looked up drug that should not be taken with Ketorolac (Toreador) on internet and see I SHOULD NOT mix Ketorolac with Ibuprofen or and NSAID or aspirin like drugs . can you tell me what will be ok to mix for pain . I have a hip and low back injury .
Answered by Dr. Muhammad Sareer Khalil 2 hours later
Brief Answer:

Detailed Answer:
Hello and Welcome

I appreciate your concern

Ketorolac, ibuprofen and aspirin are NSAIDs. Ibuprofen at the dose you described in combination with ketorolac should not be exceeded further. Aspirin should not be used. This combination is potentially nephrotoxic and can lead to gastritis too. PPIs like lansoprazole should be added to prevent gastritis or peptic ulceration due to NSAID use.

The OTC option that can be combined safely is acetaminophen or paracetamol 1 g twice or thrice a day based on severity.

Paracetamol in combination with tramadol is also available though it would require a prescription, in most setups. You may ask your doctor to consider this option. Another safe option is pregabalin or gabapentin. Either one can be taken safely with ketorolac and ibuprofen.

Wishing you best of health


Please consult your doctor before deciding on any further course of action.

For future follow up / correspondence you may ask me directly at the link given below

Dr. M.S. Khalil

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
Follow up: Dr. Muhammad Sareer Khalil 10 minutes later
Thank you very much .
Answered by Dr. Muhammad Sareer Khalil 8 hours later
Brief Answer:
Most welcome

Detailed Answer:
You are most welcome .
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

The User accepted the expert's answer

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