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Can Tramadol and Promethazine be taken together?

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Posted on Tue, 17 May 2016
Question: I took a tramadol 3.5 hours ago. Could I take half ptomethazine?
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Answered by Dr. Robert Galamaga (1 hour later)
Brief Answer:
Considerations

Detailed Answer:
hello and thank you for sending the question.

I would not take promethazine at this time. Both of these medications can lower the threshold for seizure.

I am concerned that if you take the promethazine that you may increase the risk of developing seizures.

I would wait at least 12 hours or more before considering taking promethazine. Also I would not take any medication without the further discussion with your primary care doctor.

Thank you again for sending your question.

Sincerely,

Dr. Galamaga
Above answer was peer-reviewed by : Dr. Prasad
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Dr. Robert Galamaga

Oncologist

Practicing since :2002

Answered : 2637 Questions

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Can Tramadol and Promethazine be taken together?

Brief Answer: Considerations Detailed Answer: hello and thank you for sending the question. I would not take promethazine at this time. Both of these medications can lower the threshold for seizure. I am concerned that if you take the promethazine that you may increase the risk of developing seizures. I would wait at least 12 hours or more before considering taking promethazine. Also I would not take any medication without the further discussion with your primary care doctor. Thank you again for sending your question. Sincerely, Dr. Galamaga