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Can Oxycodone,Nabumetone,Ibuprofen And Cyclobenzaprine Be Taken Together?

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Posted on Wed, 14 May 2014
Question: i took oxycodone, nabumetone, ibuprofen, and cyclobenzaprine, is that bad?
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Answered by Dr. Praveen (2 hours later)
Brief Answer:
Potassium and coagulation need close monitoring

Detailed Answer:
Hi.Thanks for giving me an opportunity for answering your query.

I were to closely monitor both coagulation parameters(by doing PT/APTT) and serum potassium levels because of the interactions of the drugs which I have mentioned below.

buprofen + nabumetone
Both increase anticoagulation(chance of bleeding).

ibuprofen + nabumetone
Both increase serum potassium.

cyclobenzaprine + oxycodone
cyclobenzaprine and oxycodone both increase sedation.

Hope this answers your query.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by : Dr. Shanthi.E
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Answered by
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Dr. Praveen

General & Family Physician

Practicing since :2008

Answered : 1055 Questions

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Can Oxycodone,Nabumetone,Ibuprofen And Cyclobenzaprine Be Taken Together?

Brief Answer: Potassium and coagulation need close monitoring Detailed Answer: Hi.Thanks for giving me an opportunity for answering your query. I were to closely monitor both coagulation parameters(by doing PT/APTT) and serum potassium levels because of the interactions of the drugs which I have mentioned below. buprofen + nabumetone Both increase anticoagulation(chance of bleeding). ibuprofen + nabumetone Both increase serum potassium. cyclobenzaprine + oxycodone cyclobenzaprine and oxycodone both increase sedation. Hope this answers your query.