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Can Circadin And HRT-Kliogest Be Taken Together?

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Posted on Fri, 21 Aug 2015
Question: I have been prescribed Circadin (melatonin) for insomnia. I notice in the consumer information that it may not be compatible with HRT (Kliogest) which I am already taking. What should I do? Just see what happens?
doctor
Answered by Dr. Olsi Taka (21 minutes later)
Brief Answer:
Interaction is minor.

Detailed Answer:
I read your question carefully and I understand your concern.

The type of interaction between the two medications is minor, actually some sources do not cite it at all. Their interaction consists in Kliogest mildly raising melatonin levels, so perhaps a lower dose may be enough to achieve its effect. If you have been prescribed a low dose under 3 mg I suggest you continue with that current dose, while if you were prescribed a higher dose perhaps you could discuss with your prescribing physician whether a lower dose could be tried first, to be increased if deemed ineffective later.

I remain at your disposal for further questions.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Olsi Taka (3 minutes later)
Thank you doctor for your comprehensive answer.
It is much appreciated.
I have only been prescribed 2mg so I guess I will 'sleep easy' now!
Thanks again.
doctor
Answered by Dr. Olsi Taka (2 hours later)
Brief Answer:
Sweet dreams

Detailed Answer:
Thank you for your feedback.

I think you will be safe from any major side effect at that dosage.

Glad to have been of help.
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Olsi Taka

Neurologist

Practicing since :2004

Answered : 3673 Questions

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Can Circadin And HRT-Kliogest Be Taken Together?

Brief Answer: Interaction is minor. Detailed Answer: I read your question carefully and I understand your concern. The type of interaction between the two medications is minor, actually some sources do not cite it at all. Their interaction consists in Kliogest mildly raising melatonin levels, so perhaps a lower dose may be enough to achieve its effect. If you have been prescribed a low dose under 3 mg I suggest you continue with that current dose, while if you were prescribed a higher dose perhaps you could discuss with your prescribing physician whether a lower dose could be tried first, to be increased if deemed ineffective later. I remain at your disposal for further questions.