Sign in with GoogleKartagener's syndrome
What is Kartagener's syndrome?
Primary ciliary dyskinesia (PCD), also known as immotile ciliary syndrome, is a rare, ciliopathic, autosomal recessive genetic disorder that causes a defect in the action of the cilia lining the respiratory tract (lower and upper, sinuses, Eustachian tube, middle ear) and fallopian tube, as well as the flagella of sperm cells.
Respiratory epithelial motile cilia, which resemble microscopic "hairs" (although structurally and biologically unrelated to hair), are complex organelles that beat synchronously in the respiratory tract, moving mucus toward the throat. Normally, cilia beat 7 to 22 times per second, and any impairment can result in poor mucociliary clearance, with subsequent upper and lower respiratory infection. Cilia also are involved in other biological processes (such as nitric oxide production), which are currently the subject of dozens of research efforts. As the functions of cilia become better understood, the understanding of PCD should be expected to advance.
Questions and answers on "Kartagener's syndrome"
abnormal cells come and go in females during pap test in my close family such as my sisters and my daughter. my sister while pregnant had them so...
MD Hi,
Welcome to HCM!
Kartageners syndrome as you mentioned has situs in versus totalis and abnormal ciliary motion of some cells in various parts of...
Hi, Doctor , iam leaving in california. iam having kartageners syndrome-situs inverses. iam suffering with cough, sputum and runny nose. iam...
MD Welcome to Healthcare Magic
Regarding cough and sputum you could be having long term infection which can cause Bronchiectasis which is irreversible...
my wife under went a 24 week anomoly scan today and the scan says situs inversus totalis. Is it safe to continue pregnancy. can the child born...
MD Hi XXXXXXX
Thank you for posting your query.
Situs inversus totalis is a condition where major visceral organs inside the body are reversed...