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On Lupron For Endometriosis Stage 3. Started Feeling Tired And Achy Legs. Should I Be Concerned?

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Posted on Fri, 9 Nov 2012
Question: Hello, I am a 28 year old female. with hx of endometriosis stage 3. I was started on lupron and add back therapy two months ago. The last several day or so i have noticed that i wake up and my legs are achy and tired like I had exercised them. I have a physical job where im contstantly moving from 8-12 hours, but my hours and workload has not changed. Should i be concerned about this tired feeling? Could it be related to the Lupron. thank you
doctor
Answered by Dr. Minoo Bhagia (1 hour later)
Hello
Welcome and thanks for the query
Lupron is GnRh analog and acts on pituitary to regulate oestrogen and testosterone levels.It is effective in the treatment of endometriosis but in some females it can cause generalized pains and weakness.Prolonged use may cause bone loss by lowering oestrogen levels.It is better to get your calcium and Vit D levels done as well as BMD.
Regular use of calcium along with Vit D is advised.As you are having PCOD along with endometriosis so it is better to get an insulin resistance test done.
I hope your thyroid levels are normal as hypothyroidism can also cause weakness in the legs.Please reply back regarding these tests as it is very difficult to pin point the cause of your symptoms without seeing the reports ,till then you can start taking vitamin B12 and Vitamin D along with calcium.Elevate the legs while sleeping.
Waiting for your reply
Best wishes
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Minoo Bhagia

OBGYN

Practicing since :1983

Answered : 979 Questions

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On Lupron For Endometriosis Stage 3. Started Feeling Tired And Achy Legs. Should I Be Concerned?

Hello
Welcome and thanks for the query
Lupron is GnRh analog and acts on pituitary to regulate oestrogen and testosterone levels.It is effective in the treatment of endometriosis but in some females it can cause generalized pains and weakness.Prolonged use may cause bone loss by lowering oestrogen levels.It is better to get your calcium and Vit D levels done as well as BMD.
Regular use of calcium along with Vit D is advised.As you are having PCOD along with endometriosis so it is better to get an insulin resistance test done.
I hope your thyroid levels are normal as hypothyroidism can also cause weakness in the legs.Please reply back regarding these tests as it is very difficult to pin point the cause of your symptoms without seeing the reports ,till then you can start taking vitamin B12 and Vitamin D along with calcium.Elevate the legs while sleeping.
Waiting for your reply
Best wishes