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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Will Metformin And Glipizide Help In Curing Lactic Acidosis And Pancreatitis?

what is lactic acidosis...how dou get this ...i am takeing medformin 500 mg 2 pills n morn plus 1pill glipizide 10 mg then in evening 2 pills metformin 500mg 1 pill glipizide 10 mg n evening....i was takein janumet 50-500 2 pills in morn with glipizide 10 mg then 2 pills janumet 50- 500n evening 1 pill gliptizide 10mg n evening ....i got pancriatitus n my doctor switched my meds he cancelled janumet n put me on metformin.....thanks marty
Wed, 18 Dec 2013
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Internal Medicine Specialist 's  Response
Hi Marty, Lactic acidosis is a condition in which a particular form of acid accumulates in the blood making it very acidic. This happens when patient has severe infection/ sepsis; or patient with kidney failure takes metformin tablets.

In your case the doctor changed your diabetes drug because, janumet has a compound called sitagliptin which has been associated with pancreatitis in studies. Hence he stopped the combination janumet and put you only on metformin with glipizide. As long as your kidneys are normal you need not worry about lactic acidosis.
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Will Metformin And Glipizide Help In Curing Lactic Acidosis And Pancreatitis?

Hi Marty, Lactic acidosis is a condition in which a particular form of acid accumulates in the blood making it very acidic. This happens when patient has severe infection/ sepsis; or patient with kidney failure takes metformin tablets. In your case the doctor changed your diabetes drug because, janumet has a compound called sitagliptin which has been associated with pancreatitis in studies. Hence he stopped the combination janumet and put you only on metformin with glipizide. As long as your kidneys are normal you need not worry about lactic acidosis.