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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Zero Sperms, Tubules Lined Only With Sertoli Cells, No Varicose, Find Sperms In Other Parts Of Testicles For ICSI. Resolution?

my husband is 26 years old & had zero sperms in semen analysis but all characters of semen is normal & he has no varicose of testicles all hormones are normal except little elevation of ( lh ) hormone f sh 9.4 l h 9.8 prolactine 9.9 total testosterone 4.6 free testosterone 19 fructose 53 ( too little so there is an obstruction) he was born with undescended left testicle that was descended at 7years old although both testicles are normal in size then made one random bilateral biopsy of testicles and the result was tubules lined only with sertoli cells with no germ cell element bilateral complete germ cell aplasia with focal tubular scelerosis & moderate leiding cell hyperplasia no evidence of specific inflamation he had no diseases like high blood preasure ,diabetes, mumps or any kidney problems he has no problems with erection of penis can we find any sperms in other parts of testicles to be used in Intracytoplasmic Sperm injection ICSI or it is impossible can we make stem cells implantation for infertility in this case ( sertoli cell only syndrome ) note.i don t have any problems that prevent me to get baby ( my period is regular ) can we have a baby or it is impossible
Fri, 22 Mar 2013
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Urologist 's  Response
Hello
Thanks for your query.Based on the facts that you have posted it appears that your husband has Azoospermia.
As his testicular biopsy shows no evidence of spermatognesis it is practically impossible for you to get any sperm from the testis for ICSI.
You have to unfortunately accept the reality. and try for other mode of being pregnant like using semen from Donor.
Advice and guidance of a qualified Infertility Specialist will be of much help to you.
Dr.Patil
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Zero Sperms, Tubules Lined Only With Sertoli Cells, No Varicose, Find Sperms In Other Parts Of Testicles For ICSI. Resolution?

Hello Thanks for your query.Based on the facts that you have posted it appears that your husband has Azoospermia. As his testicular biopsy shows no evidence of spermatognesis it is practically impossible for you to get any sperm from the testis for ICSI. You have to unfortunately accept the reality. and try for other mode of being pregnant like using semen from Donor. Advice and guidance of a qualified Infertility Specialist will be of much help to you. Dr.Patil