Dear Doctor, I have been facing depression and anxiety/panic related problems for the last 2 years, and my family physician prescribed me serlift 25 (Sertralin) once daily. However, after taking serlift 25 for a week, my depression, anxiety got worsen. Is this a normal symptom, or should I discontinue this drug. Regards Biswadip (India) Age - 38 Years, Weight - 85 kg.