Sir/Madam, I am 40, female. I have pefectly regular periods. I used to have acne/pimples just one week before my periods and it lasts for a week. But for the last three months, I have pimples regularly. This time it is different, it is itchy, with white colour puss like , painful, skin becomes thick too. Though my doctors gave different treatment like propysalic NF, Clindamycin, some tablets, nothing seems to work. I need your help.