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What Is My Pap Smear Test Result Suggestive Of?
hi i would be very thankfull if you can help me with this. my mother 60 years old had pap smear rhat return abnormal with atypical grandular cells probably reactive, what does it means, is it sign for precancer or cancer, and as well she has infections such as trochicomas vaginilis, and plus in her ultrasound report is mention cervical hyperehogenic 13 mm, what does it mean? she will go for some currtage and biopsyfrom uterus and cervix.
Wed, 8 May 2019
Hello,
Atypical glandular cells on Papanicolaou smears(PAP smears) are an unusual but important cytologic diagnosis.
The Bethesda system classifies atypical glandular cells of undetermined significance (AGUS) as glandular cells that demonstrate nuclear atypia appearing to exceed reactive or reparative changes but lacking unequivocal features of adenocarcinoma.
AGUS occurs in approximately 0.18 to 0.74 percent of all cervical smears.
Because of the high likelihood that AGUS is associated with significant clinical disease, simply repeating the Papanicolaou smear is not sufficient for the management of AGUS.
Unlike women with atypical squamous cells of undetermined significance, a significant percentage of women with AGUS will have more serious lesions, such as high-grade preinvasive squamous disease, adenocarcinoma in situ, adenocarcinoma or invasive cancers from sites other than the cervix.
The colposcopic examination is recommended for all women with a cytologic diagnosis of AGUS.
Those women with AGUS that is suspicious for adenocarcinoma should undergo cervical conization, even in the absence of detectable abnormalities on colposcopic examination.
Hope I have answered your query. Let me know if I can assist you further.
Take care
Regards,
Dr Naira Jahangir, OB and GYN Specialist
Atypical glandular cells on Papanicolaou smears(PAP smears) are an unusual but important cytologic diagnosis.
The Bethesda system classifies atypical glandular cells of undetermined significance (AGUS) as glandular cells that demonstrate nuclear atypia appearing to exceed reactive or reparative changes but lacking unequivocal features of adenocarcinoma.
AGUS occurs in approximately 0.18 to 0.74 percent of all cervical smears.
Because of the high likelihood that AGUS is associated with significant clinical disease, simply repeating the Papanicolaou smear is not sufficient for the management of AGUS.
Unlike women with atypical squamous cells of undetermined significance, a significant percentage of women with AGUS will have more serious lesions, such as high-grade preinvasive squamous disease, adenocarcinoma in situ, adenocarcinoma or invasive cancers from sites other than the cervix.
The colposcopic examination is recommended for all women with a cytologic diagnosis of AGUS.
Those women with AGUS that is suspicious for adenocarcinoma should undergo cervical conization, even in the absence of detectable abnormalities on colposcopic examination.
Hope I have answered your query. Let me know if I can assist you further.
Take care
Regards,
Dr Naira Jahangir, OB and GYN Specialist
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