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What happens in metabolic acidosis ?

please explain to me in layman s term what is metabolic acidosis is about... especially the pathophysiology of this disorder.. what is anion gap? and its formula? please respond thank you and GOD BLESS!
Asked On : Wed, 29 Jun 2011
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Orthopaedic Surgeon 's  Response
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Metabolic acidosis is when the body acids are more in the body, like lactic acid, aceoacetic acid etc. It happens in metabolic disorders like Lactic acidosis and uncontrolled Diabetes which causes Diabetic ketoacidosis respectively.

Anion gap is the unmeasurable anions in the blood which is contributing to acidosis.

Formula is [Na + K]-[Cl + HCO3] ions.

Normal is 10-12mEg/L

Higher the acids in the blood, more is the Anion gap

Answered: Wed, 29 Jun 2011
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