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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Does AST-45 And ALT-77 In Liver Function Test Suggest?

I have been taking 20 mg of pravachol daily for 3 years. My alt and ast blood levels have always been in the 30 s. They are now AST 45 and ALT 77. I am 60 years old 6 feet tall and weigh 182 lbs. The balance of my bloodwork is normal. I reacently had an ultrasound and everything came back normal. No iron issues or hepatits A,B or C . My dr is no concerned and says we will recheck in 6 months unless I have any symptoms. Do you concur with thi approach.
Fri, 13 Mar 2015
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General & Family Physician,  's  Response
Hi
Thanks for choosing HCM for your query.

I really appreciate your concern for mildly elevated liver enzymes.
Typically the range for normal AST is between 10 to 40 units per liter and ALT between 7 to 56 units per liter.

Pravachol which is used in the treatment of high cholesterol is known to cause injury to the liver which is reflected in the form of elevated liver enzymes.

In view of the normal ultrasound, blood work, and normal hepatitis virus profile there is slight elevation which needs to be monitored and correlated with the signs and symptoms.
Kindly visit your doctor for possible use of alternative drug for high cholesterol or reduction in the dose of Pravachol.

I hope your doubts have been clarified.
Kindly give your feedback if convinced.
Take care.
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What Does AST-45 And ALT-77 In Liver Function Test Suggest?

Hi Thanks for choosing HCM for your query. I really appreciate your concern for mildly elevated liver enzymes. Typically the range for normal AST is between 10 to 40 units per liter and ALT between 7 to 56 units per liter. Pravachol which is used in the treatment of high cholesterol is known to cause injury to the liver which is reflected in the form of elevated liver enzymes. In view of the normal ultrasound, blood work, and normal hepatitis virus profile there is slight elevation which needs to be monitored and correlated with the signs and symptoms. Kindly visit your doctor for possible use of alternative drug for high cholesterol or reduction in the dose of Pravachol. I hope your doubts have been clarified. Kindly give your feedback if convinced. Take care.