The possible diagnoses for a patient presenting with persistent nausea and/or vomiting are many and varied, but in the main may be considered: Visceral disease Metabolic or toxic Central nervous system disease Psychiatric illness Gastroparesis (a condition in which the muscles of the stomach wall don t function properly, interfering with digestion) General anesthesia Migraine Other possible causes of nausea and vomiting include: Alcohol use disorder Anaphylaxis (in children) Anorexia nervosa Appendicitis Benign paroxysmal positional vertigo (BPPV) (both cancerous and noncancerous) Bulimia nervosa Concussion Cholecystitis Crohn s disease Cyclic vomiting syndrome Depression.