Hi while taking medication for gout in October last year 2010, the doctor thought it best to check my liver enzymes before prescribing the relevant NSAID. At that time I showed slightly raised AST/ALT levels but not enought to prevent prescription of NSAID (AST-42 / ALT-65). After about taking NSAID for a little more than a month and periodic gout attacks in between, I took the last prescription in Dec 2010 for around one week. In Jan during a follow up when we checked on the liver enzymes, the AST had slightly come down but ALT was up to 70. I also took Colchicin from Jan till around Feb 15. Now, last week (Mar 2011) I had a retest on my liver but with all functions - in this AST is 57 and ALT is 99. However, all other liver function blood tests are absolutely within normal range. Is this something to be concerned about? How do I reduce AST and ALT? I am currently taking an herbal drug called LEGALON which is said to prevent liver damage. I have also had an abdominal USG done at which time other than a gassy colonic area I was shown to have grade 2 fatty liver. I used to drink a lot - but in July 2010 I quit alcohol and did so until Dec 2010. I restarted in Jan 2011 but my consumption is minimal - maybe a couple of pegs per week. I am also on a diet and exercise regularly for 1.5 hrs everyday. I am overweight / obese at 115kgs. I am concerned about the trend in my ALT from 65 to 70 to 99 when my diet has been brought to some level of control and coupled with exercise as well. I have increased proteing intake and am told this could be a reason as well? Could you throw any light on this?