Dear thanks for the question. Tiredness for one odd day may not be so significant but since you always feel so, if I were your treating doctor I would have done a blood work up for anaemia (low haemoglobin) and infections, thyroid work up for hypothyroidism (reduced functioning), liver function test . Depending on those results I would have given treatment. I would like to advise you to visit a general physician in your area and under go examination. Till than improve on your fluid intake, increase fruit intake, no to alcohol, start morning exercises, be happy. I hope I have clarified your queries. I would love to reply follow up queries. Rate my reply. I wish you good health. Thank you.