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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side Effects Of Taking Tramadol And Methdone?

I have severe tooth ache and dentist is suggesting surgery because my wisdom tooth is wrapped around my jaw bone.He suggested a pain medication called tramadol for the pain. However, I have been on 150 mg daily of methadone for about 3 years. Please explain the side effects if I were to take tramadol and methdone when I get surgery and if you would suggesst some safe pain killer instead. Thank you
Fri, 17 Apr 2015
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General & Family Physician,  's  Response
hi.
methadone ↔ tramadol
GENERALLY AVOID: Concomitant use of tramadol increases the seizure risk in patients taking other opioids. These agents are often individually epileptogenic and may have additive effects on seizure threshold during coadministration. CNS- and respiratory-depressant effects may also be additive. In patients who have been previously dependent on or chronically using opioids, tramadol can also reinitiate physical dependence or precipitate withdrawal symptoms.
thank you.
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What Are The Side Effects Of Taking Tramadol And Methdone?

hi. methadone ↔ tramadol GENERALLY AVOID: Concomitant use of tramadol increases the seizure risk in patients taking other opioids. These agents are often individually epileptogenic and may have additive effects on seizure threshold during coadministration. CNS- and respiratory-depressant effects may also be additive. In patients who have been previously dependent on or chronically using opioids, tramadol can also reinitiate physical dependence or precipitate withdrawal symptoms. thank you.