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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side Effects Of Apoquel?

I have been trying to research the side effects of Apoquel and it said Xeljanz was the human equivalent of it. All I find onApoquel is the research results but no real list of side effects so thought i would look at Xeljanz side effects and it seems a bit general. Are these drugs fairly new?
Wed, 12 Apr 2017
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General & Family Physician,  's  Response
Hi & Welcome.

These are new drugs which belong to the class of drugs called Janus Kinase (JAK) inhibitors.

However, Apoquel (Oclacitinib) tablet is effective in controlling itching associated with allergies and hence used for the treatment of chronic manifestations of atopic dermatitis in dogs.

Its side effects include diarrhea, vomiting, anorexia, and/or lethargy. There can be an increased risk of infections in dogs treated with Oclacitinib.

Whereas Tofacitinib (Xeljanz) is a biologic agent used in the treatment of moderate-to-severe, active rheumatoid arthritis who have not responded well to being treated with Methotrexate.

It may be used alone or in combination with Methotrexate or other disease modifying anti-rheumatoid drugs.
Its most common side effects are upper respiratory tract infections, diarrhea, headache, nasal congestion, sore throat and runny nose.

It can also lower body’s ability to fight infections, including tuberculosis, infections caused by bacteria, fungi, or viruses that can spread throughout the body.

Hope to have answered your queries.
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What Are The Side Effects Of Apoquel?

Hi & Welcome. These are new drugs which belong to the class of drugs called Janus Kinase (JAK) inhibitors. However, Apoquel (Oclacitinib) tablet is effective in controlling itching associated with allergies and hence used for the treatment of chronic manifestations of atopic dermatitis in dogs. Its side effects include diarrhea, vomiting, anorexia, and/or lethargy. There can be an increased risk of infections in dogs treated with Oclacitinib. Whereas Tofacitinib (Xeljanz) is a biologic agent used in the treatment of moderate-to-severe, active rheumatoid arthritis who have not responded well to being treated with Methotrexate. It may be used alone or in combination with Methotrexate or other disease modifying anti-rheumatoid drugs. Its most common side effects are upper respiratory tract infections, diarrhea, headache, nasal congestion, sore throat and runny nose. It can also lower body’s ability to fight infections, including tuberculosis, infections caused by bacteria, fungi, or viruses that can spread throughout the body. Hope to have answered your queries.