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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Taking Diane-35 For Acne. Will Zinc Be Effective Substitute To Diane-35? How To Stop Dependency On The Medicine?

I ve had stress acne on face since four years ( am now 26+) and was put on Diane-35 a couple of years back. As major improvements have occurred since last 6 months, I want to wean off now. But fears of relapse is still there, as I am not too good at handling stress. I ve come across medical reports citing Zinc as an effective substitute to regulate hormonal levels in body , thus reducing chances of breakouts. I wish to confirm this news and, which Indian pharmaceutical provides zinc capsules for the same. What steps should I follow to completely free my body from dependence on Diane- 35?
Wed, 3 Apr 2013
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General & Family Physician,  's  Response
Hi thanks for asking in Healthcare Magic.

Acne is due to infection and the resultant inflammation of sebaceous gland. This leads to blockage of hair follicles and accumulation of sebum.
Diane-35 contains Cyproterone acetate (anti androgen) and ethinyl estradiol (estrogen). This is useful only in women suffering from hirsutism (male pattern hair growth in face). It results in many unwanted side effects as it contains hormones.
Zinc may be useful as it is a known antiseptic and astringent (precipitates surface bacterial proteins). It is used as a cosmetic and soothing agent in many skin conditions but the dose needed in acne may be higher and this may result in unwanted side effects.
Instead of taking oral medication (tablets) you can try using topical applications for acne. Adapalene ointment will be very effective in reducing the inflammation. Benzyl peroxide ointment is another useful alternative.
But both Adapalene and Benzyl Peroxide should not be used together.

I hope this is useful.
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Taking Diane-35 For Acne. Will Zinc Be Effective Substitute To Diane-35? How To Stop Dependency On The Medicine?

Hi thanks for asking in Healthcare Magic. Acne is due to infection and the resultant inflammation of sebaceous gland. This leads to blockage of hair follicles and accumulation of sebum. Diane-35 contains Cyproterone acetate (anti androgen) and ethinyl estradiol (estrogen). This is useful only in women suffering from hirsutism (male pattern hair growth in face). It results in many unwanted side effects as it contains hormones. Zinc may be useful as it is a known antiseptic and astringent (precipitates surface bacterial proteins). It is used as a cosmetic and soothing agent in many skin conditions but the dose needed in acne may be higher and this may result in unwanted side effects. Instead of taking oral medication (tablets) you can try using topical applications for acne. Adapalene ointment will be very effective in reducing the inflammation. Benzyl peroxide ointment is another useful alternative. But both Adapalene and Benzyl Peroxide should not be used together. I hope this is useful.