Excellent questions. First things first: if you are abusing any substance, whether an illegal drug or prescription medication, this needs to be addressed before anything else. Adding antidepressants will not help you if you are abusing or withdrawing from substances. If this is the case, I recommend detox and rehab before addressing
depression,
anxiety, or ADHD.
You describe a history of anxiety and depression. We'll leave ADHD aside for a moment. The standard treatment for both depression and anxiety is either an antidepressant,
psychotherapy, or both in combination, which is usually the most effective. It sounds like you started taking Celexa, after a month you noticed no change, and
Wellbutrin was added. This is a sound strategy. Keep in mind that unfortunately, you may not notice an improvement in symptoms using an antidepressant for 4-6 weeks. It requires some patience to allow time for the medication to work, and if it doesn't work, to increase doses and employ augmentation strategies like adding Wellbutrin to the mix. If you are still not feeling better after 4-6 weeks of maximum dose Celexa + maximum dose Wellbutrin, I would switch to a different antidepressant (Zoloft, Lexapro, Prozac, etc) and give that a try.
I would not under any circumstances ever use Xanax, for a couple reasons. First, benzodiazepines actually do not treat anxiety well in the long term; this is the job of an antidepressant. Second, Xanax is a highly addictive benzodiazepine, which should be avoided at all costs in someone with a history of
substance abuse. As you mention, you will habituate (develop tolerance to) this medication quickly, and it will not help you in the long-term.
I would avoid treatment of ADHD until your mood and anxiety disorders are addressed. These are causing you the most trouble, and ADHD treatment is tricky because it also involves
amphetamines, which are addictive substances.
In summary, I would avoid benzodiazepines altogether, set aside ADHD for the moment, and focus on depression and anxiety. This involves treatment with an antidepressant and, if possible, psychotherapy. Allow 4-6 weeks of maximum-dose antidepressant to work, and if it doesn't, augment with something like Wellbutrin or
lithium, or switch to a different antidepressant. There are many to choose from, so be hopeful. I'm sure with time and patience you will begin to feel better.
Dr. Sheppe