I have been very depressed even more than usual. I have had Multiple Sclerosis for 21 years, and I can still do many things like walk, drive, etc. I cannot work, because I was a social worker and I had a hard time with home visits due to getting up steps at certain houses. I ve not worked since 2003. I am on Effexor EX, but I am still very depressed. I would not hurt myself because I have 3 dogs I love very much, and I have my mom. My husband left me when I had MS for 7 years. He was too weak to take it. Now my best friend of many years will not talk to me because we don t agree on politics! People tell me she was a TRUE friend. But I m still depressed and have no energy at all!