Hi, your question has a complex answer and therefore the delay in some medical answer it, but I'll try to help you.
The overall picture you describe suggests that doctors are treating his wife to
severe angina. Angina is caused by a significant obstruction in one or more coronary arteries. To confirm these obstructions is necessary to do a
coronary catheterization and thus organize a definitive treatment.
There are four forms of treatment for patients with blocked coronary arteries:
1- Clinical treatment: Made with medications that reduce
metabolism and
oxygen consumption of the heart muscle, as well as medications that dilate these arteries.
2- Coronary Angioplasty: It is usually used for patients with one or two obstructions in arteries and consists of placing a
stent device at the site of obstructions by facilitating local blood flow.
3- surgery for revascularization of myocardium: Used for patients with unfavorable obstructions angioplasty, with better results in the long term in relation to the placement of stents.
4- Cardiac transplantation: It is only indicated in extreme cases, when none of the above treatments are possible or effective, associated with significant worsening of cardiac function. It is the least common treatment used.
If the optimal medical treatment is not working well, the ideal is to evaluate the possibility of using one of the other alterative described above.
Hope I have answered your question. If you have any further questions I will be happy to help you. Wish you good health.