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Suffered DAI/TBI. Difficulty recollecting events, aggressive, sleeplessness, loose bladder control, salivation. Can anti-depressants and sedatives be given?

URGENT:After DAI/TBI (in RTA on 05.02.2012) may sister (29years) is able to recollect historical & home-events. Now she is GCS-E4M6V4 for past one week however she becomes aggressive & sleep-less (sleeps for one night after 2days & 2 nights). sometimes saliva do comes out & she is able to tell urine & stool sensations. Tracheostomy was removed 3-weeks ago. Should we give anti- depression or Sedatives to calm her? what is difference between the two? how long more she will take to recover? Puneet (PhD, B.Tech, MBA)
Tue, 3 Jul 2012
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General & Family Physician 's  Response

YOur sister almost recovered upto 90%. The prognosis from this stage is extremely hopeful. Since the GCS is 14, the aggressive ness can be attributed to drugs, irritability.

You may consult the doctor to give low dose sedatives to calm her.

We cannot predict the time for recovery exactly as it depends on number of factors like the amount of injury, time to regain consiousness, the time taken to institute the treatment etc.

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General & Family Physician Dr. Aparna Kohli's  Response
Hi Puneet,
I am sorry about your sister.
Your sister probably has delirium in which people often find it difficult to sleep. She needs sedatives under the guidance of your physician, because given her condition , you should not take the chance of giving anything to her on your own.
Anti-depressants are used to treat depression, while sedatives induce sleep. They are different drug classes altogether.
It should take considerable time for her to recover since Diffuse axonal injury is a very severe injury.
I wish you all the strength to deal with this.
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