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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Simvastatin Or Rosuvastatin Cause High SGPT And SGOT?

Hi doc, Last one I undergo some blood chem due to my high blood pressure . and it find out during the test that the Fasting Blood Sugar , Cholesterol and Triglycerides are above normal limits. Then the doctor give me a medication called rosovastatin. After a month (thats is today) I decided to check again my Cholesterol level and Triglycerides. I undergo again the same test. and the good news is my cholesterol and Triglycerides are on normal but the bad news is my SGPT/ ALT (114) and SGOT/AST (131) are to high. What will I do doc to prevent to lower my SGPT and SGOT? Is simvastatin or rosovastatin can trigger to high the SGPT and SGOT?
Tue, 15 May 2012
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Gastroenterologist, Surgical,  's  Response
Long term use of statins is injurious to the liver and muscle. The raised enzymes can be attributed to the usage of statins.I would suggest you to stop statins and start alternative medications. Most important would be strict dietary modifications along with regular exercise.
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Simvastatin Or Rosuvastatin Cause High SGPT And SGOT?

Long term use of statins is injurious to the liver and muscle. The raised enzymes can be attributed to the usage of statins.I would suggest you to stop statins and start alternative medications. Most important would be strict dietary modifications along with regular exercise.