My 76 yr old husband was often highly disorientated until he stopped taking statins; although he still has short-term memory issues, he no longer goes to the wrong room, or the wrong drawer; he no longer has to keep asking where we are when out. He has not had any problems with his heart and his cholesterol levels were only ever marginally high. Also his diet has much less meat in it now and he has reduced his drinking dramatically to 5-6 units per week and has stopped smoking. We feel he is much better off without the statins, but how can this be evaluated sensibly? What tests could a doctor use to check if the discontinuation is causing serious harm?