Hi my mother has osteoarthritis in her knee joint . Doctor has aspirated the fluid and inject cortico steroids few months ago. Now she is on glucosamine condroiton, tramadol,orphenidine, dosulepin 25mg OD, calcium and vitamin D, omeprazole,losartan +hydrochlorthiazide and atenolol. I have noticed that her palms looks a bit bluish or blackish. Can u suggest what is the cause?