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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Lump In The Breast, Ultrasound Showed Fibroadenomas But Not On The Site Of Lump, Elevated CA15-3 Value. Family History Of Breast Cancer. Additional Tests Required?

I m a 26 year old female. My mother was diagnosed with triple negative breast cancer at age 52 and died at age 54. I m currently feeling a sort of lump/thickening of the tissue on my right breast. I ve been to 2 gynecologists and they both told me it was most likely normal tissue because it s smooth, slippery and mobile and seems to be part of a larger portion of breast tissue. I have had an Ultrasound and it shows two small fibroadenomas (both 6mm), one in each breast but found nothing in the position where I can feel the tissue thickening. I have also taken a CA 15-3 test which came at 19.5. I have previously taken this test 5 years ago and the result was 11.6. These tests were taken at different laboratories. I am worried that this elevation might mean I have cancer and that 19.5 is a rather high value. My question is - is it likely that I have breast cancer? Is 19.5 a high value for me - especially since 5 years ago a test showed 11.6? Should I do any additional testing?
Mon, 25 Jun 2012
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Oncologist, Radiation,  's  Response
see tumor markers per say plays insignificant role in detection of breast cancer, having said you have family history of breast cancer you have to take extra precaution to have regular screening of breast as well as ovary+uterine body cancers. for final confirmation of cancer of breast require triple test: 1)clinical examination of breast by expert physician/surgeon 2) mammosonography of breast of both side 3) FNAC/ Biopsy from suspected lump in breast. in any doubt clinically go for mammography +/- FNAC after report of mammography. so dont worry your CA15-5 AND CA19.5 elevated tumor marker report.
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Lump In The Breast, Ultrasound Showed Fibroadenomas But Not On The Site Of Lump, Elevated CA15-3 Value. Family History Of Breast Cancer. Additional Tests Required?

see tumor markers per say plays insignificant role in detection of breast cancer, having said you have family history of breast cancer you have to take extra precaution to have regular screening of breast as well as ovary+uterine body cancers. for final confirmation of cancer of breast require triple test: 1)clinical examination of breast by expert physician/surgeon 2) mammosonography of breast of both side 3) FNAC/ Biopsy from suspected lump in breast. in any doubt clinically go for mammography +/- FNAC after report of mammography. so dont worry your CA15-5 AND CA19.5 elevated tumor marker report.