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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is This Abdominal CT Scan Test Result Relevant To Identify Pancreatic Cancer Analysis?

Lipase is 767. Amylase is 136. Abdominal CT scan showed no masses but mild calcification in aortoriliac atheroscleroeic disease. Total cholesterol 247. Which is more concerning? The enzyme level? What else can make it that high? My GP acted very serious and said he was worried about pancreatic cancer prior to the CT. Is the CT an adequate test? Should I ask for another test? My GP wants to wait another 30 days to recheck and I m not sure that is a good idea.
Fri, 5 May 2017
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General Surgeon 's  Response
Hi, I had gone through your question and understand your concerns.

As a liver and pancreatic surgeon I can say that almost all pancreatic cancers should be detectable at CT scan especially if elevated pancreatic enzymes already developed. I think that at this point there are no many factors which are suggestive of pancreatic cancer,however you should do some other tests, at least bilirubin levels and CA 19-9 markers which is marker of pancreas cancer.
Amylase and Lipsae are enzymes which are elevated in any other pancreatic disease including inflammation, cyst, chronic pancreatitis or some rare intestinal disorders. Most commonly we see it in chronic pancreatitis. This is treated by alcohol avoidance and you should eat less fatty food, less sugar and more vegetables and boiled food.

I suggest to repeat blood tests in 4 weeks and do Ca19-9 and repeat abdominal ultrasound, not CT. This should be enough to rule out malignancy.

Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us.

Wishing you good health.
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Is This Abdominal CT Scan Test Result Relevant To Identify Pancreatic Cancer Analysis?

Hi, I had gone through your question and understand your concerns. As a liver and pancreatic surgeon I can say that almost all pancreatic cancers should be detectable at CT scan especially if elevated pancreatic enzymes already developed. I think that at this point there are no many factors which are suggestive of pancreatic cancer,however you should do some other tests, at least bilirubin levels and CA 19-9 markers which is marker of pancreas cancer. Amylase and Lipsae are enzymes which are elevated in any other pancreatic disease including inflammation, cyst, chronic pancreatitis or some rare intestinal disorders. Most commonly we see it in chronic pancreatitis. This is treated by alcohol avoidance and you should eat less fatty food, less sugar and more vegetables and boiled food. I suggest to repeat blood tests in 4 weeks and do Ca19-9 and repeat abdominal ultrasound, not CT. This should be enough to rule out malignancy. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. Wishing you good health.