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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Treat VDRL+TPHA Being Positive?

My son was diagnosed as VDRL+TPHA psitive in April this year.He was treated with penicillin.In the month of july his VDRL became negative.But after two months in the same Laboratory it again became positive.What is this ,please let me know the permanent treatment for this.
Fri, 5 Sep 2014
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Pathologist and Microbiologist 's  Response
Hi,
Thanks for asking.
Based on your clinical history and query, my opinion is as follows:
1. VDRL is a screening test. Its based on presence of antibodies.
2. VDRL and TPHA positive means definitely syphilis and he is treated for that.
3. However, his antibodies would be persistent and hence he will remain VDRL positive for life. He is negative for current infection. Not to worry.
Hope it helps.
Any further queries, happy to help again.
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How To Treat VDRL+TPHA Being Positive?

Hi, Thanks for asking. Based on your clinical history and query, my opinion is as follows: 1. VDRL is a screening test. Its based on presence of antibodies. 2. VDRL and TPHA positive means definitely syphilis and he is treated for that. 3. However, his antibodies would be persistent and hence he will remain VDRL positive for life. He is negative for current infection. Not to worry. Hope it helps. Any further queries, happy to help again.