Hi, welcome to our site. I am Dr Saumya Mittal. Read your query. That is a very significant question and i appreciate your problem. I will try my best to answer your query I am not quite sure what exactly you need to ask. I mean your question seems to ask if metformin can increase the sugars. Well you know of course, since you take the medicine for diabetes, that metformin only reduces the blood sugars. As for the cause of raised sugars, it is obvious and you have given the reason yourself in the question. If you take 2 doses at one time, it does not mean that you skip the dose in the evening. It means that you need to check the sugars at the time when the second dose is scheduled and modify the dose according to the reading on the glucometer. If you skip the dose, the sugars are going to rise. Besides, you obviously took your meal. So the sugars are going to rise, and will not be the same. Will not be same as the fasting levels. The post prandial sugar in a well controlled diabetic is usually higher than the fasting levels. Alternatively, you may do nothing and continue the regular dose and schedule starting the next day. Check sugars again in 3 days I hope this helps you. Inform the reports mentioned above so i can be of help further. Best of luck. I have given you the answer to the maximum considering the information provided. The results of the tests could further enhance my answer to you. Please do understand that some details could be extracted from a detailed history and examination. Looking forward to your return query with the details asked so that I can help you further. (If the answer has helped you, please indicate this)