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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Estradiol Cause Water Retention In The Arms And Legs?

I have used vivelle dot for 5 years and about six weeks ago switched to estradiol because my health care would not cover the cost of vivelle dot. I have noticed some changes in my body and I am wondering if these changes are normal. My arms,legs and torso seem to be fuller like they are holding water. I have low energy and some head aches . Just wondering if this is typical
Wed, 28 Apr 2021
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General & Family Physician,  's  Response
Hi,

Estradiol is a form of estrogen, a natural female sex hormone that is used in the treatment of menopause symptoms like hot flashes, vaginal changes such as vaginal dryness, burning or itching etc., and in the prevention of osteoporosis or bone loss in menopausal women which are caused by the body making less estrogen. But, like other medications, Estradiol has some side effects too. It may cause swelling of lips, tongue, throat, face, eyes, hands or feet due to retention of fluids.

It may also cause headache, sweating, unusual tiredness and weakness, exhaustion, fatigue, lack of energy, dizziness, drowsiness, breast tenderness and enlargement, mood swings, depression, allergic reactions etc. These side effects are mild and self limiting as well as go away eventually as your body adjusts to this medication. But, if these side effects persist for long or bother you, then you should consult your doctor first for medical help.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician
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Does Estradiol Cause Water Retention In The Arms And Legs?

Hi, Estradiol is a form of estrogen, a natural female sex hormone that is used in the treatment of menopause symptoms like hot flashes, vaginal changes such as vaginal dryness, burning or itching etc., and in the prevention of osteoporosis or bone loss in menopausal women which are caused by the body making less estrogen. But, like other medications, Estradiol has some side effects too. It may cause swelling of lips, tongue, throat, face, eyes, hands or feet due to retention of fluids. It may also cause headache, sweating, unusual tiredness and weakness, exhaustion, fatigue, lack of energy, dizziness, drowsiness, breast tenderness and enlargement, mood swings, depression, allergic reactions etc. These side effects are mild and self limiting as well as go away eventually as your body adjusts to this medication. But, if these side effects persist for long or bother you, then you should consult your doctor first for medical help. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Zubayer Alam, General And Family Physician