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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Ibuprofen Cause Cloudy Urine?

I had a complete knee replacement a month ago and to get swelling down (as well as applying ice often) I m taking 600 mg. of Ibuprofin every 4 or more hours around the clock. My urine has been cloudy for over a week--with no other indications of a bladder infection. Can Ibuprofin cause this?
Mon, 2 Jan 2017
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General & Family Physician 's  Response
Hello and welcome to ‘Ask A Doctor’ service.

I have reviewed your query and here is my advice.

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). It is used to treat pain or inflammation caused by many conditions. Commonly encountered side effects of ibuprofen include hemorrhage, vomiting, anemia, decreased hemoglobin, eosinophilia and hypertension. Other side effects include upper gastrointestinal hemorrhage, upper gastrointestinal tract ulcer, dizziness and dyspepsia.

Although it is not known to cause renal toxicity, long-term administration of high doses could result in renal papillary necrosis and injury to the renal tissues. Since you are having certain symptoms related to renal system, it would be better to undergo the following investigations to know what could be the cause for cloudy urine:

1. Ultrasound scan of the abdomen.
2. Urine routine examination.

Kindly consult a nephrologist with the report for clinical evaluation and management.

Hope the information provided would be helpful. Let me know if I can assist you further.

Regards,
Dr. Ashakiran S
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Can Ibuprofen Cause Cloudy Urine?

Hello and welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID). It is used to treat pain or inflammation caused by many conditions. Commonly encountered side effects of ibuprofen include hemorrhage, vomiting, anemia, decreased hemoglobin, eosinophilia and hypertension. Other side effects include upper gastrointestinal hemorrhage, upper gastrointestinal tract ulcer, dizziness and dyspepsia. Although it is not known to cause renal toxicity, long-term administration of high doses could result in renal papillary necrosis and injury to the renal tissues. Since you are having certain symptoms related to renal system, it would be better to undergo the following investigations to know what could be the cause for cloudy urine: 1. Ultrasound scan of the abdomen. 2. Urine routine examination. Kindly consult a nephrologist with the report for clinical evaluation and management. Hope the information provided would be helpful. Let me know if I can assist you further. Regards, Dr. Ashakiran S