I have been prescribed amitriptyline (10mg) for sciatica. However, I also take omeprazole (20mg) for refulx that I ve suffered with for 10 plus years. I have been told by someone that talking both medications at the same could kill you. Is this true and if so why? I also suffer with chronic asthma that I was born with and I am currently on Ventolin and Seretide and my asthma is fairly well controlled. I have for the moment stopped taking the omeprazole as I am trying to come off it anyway but thought I would now especially after hearing about the 2 drugs together.