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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Docusate Be Taken Along With Verapamil?

I have a right ventricular outflow tract arrhythmia and am on verapamil. I am experiencing constipation as a side effect of the medication. I have tried various fruit and fiber, more water, prunes without much success. Is it advisable to take a laxative such as docusate/sennosides? (the label says Sennosides is a stimulant - will that increase the cardiac arrhythmia?) Thank You, Gail
Wed, 21 Sep 2016
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General & Family Physician 's  Response
As such there is no significant drug interaction between verapamil and docusate. Docusate is a stimulant laxative. Stimulant laxatives are substances that act on the intestinal mucosa increasing water and electrolyte secretion in gut causing softening of stool. Stimulant laxative does not stimulate heart and does not cause cardiac arrhythmia.
You can try with lactulose. It is a better laxative.
Advice
1.     Syrup lactulose 2 teaspoonful per oral at bed time
2.     Continue verapamil as suggested by your doctor
3.     Take high fiber diet such as split peas, lentils, black beans, lima beans, baked beans, whole grains, vegetables such as artichoke, green peas, and sprouts and fruits
4.     Drink 4 – 5 liters of water daily
5.     Avoid straining while defecating
6.     Regularly go to toilet. Never avoid if you feel pressure
7.     Avoid excess intake tea and coffee after meal if tea and coffee contain tannins which cause constipation
Thanks
I find this answer helpful
General & Family Physician Dr. Nishikant Verma's  Response
As such there is no significant drug interaction between verapamil and docusate. Docusate is a stimulant laxative. Stimulant laxatives are substances that act on the intestinal mucosa increasing water and electrolyte secretion in gut causing softening of stool. Stimulant laxative does not stimulate heart and does not cause cardiac arrhythmia.
You can try with lactulose. It is a better laxative.
Advice
1.     Syrup lactulose 2 teaspoonful per oral at bed time
2.     Continue verapamil as suggested by your doctor
3.     Take high fiber diet such as split peas, lentils, black beans, lima beans, baked beans, whole grains, vegetables such as artichoke, green peas, and sprouts and fruits
4.     Drink 4 – 5 liters of water daily
5.     Avoid straining while defecating
6.     Regularly go to toilet. Never avoid if you feel pressure
7.     Avoid excess intake tea and coffee after meal if tea and coffee contain tannins which cause constipation
Thanks
I find this answer helpful

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Can Docusate Be Taken Along With Verapamil?

As such there is no significant drug interaction between verapamil and docusate. Docusate is a stimulant laxative. Stimulant laxatives are substances that act on the intestinal mucosa increasing water and electrolyte secretion in gut causing softening of stool. Stimulant laxative does not stimulate heart and does not cause cardiac arrhythmia. You can try with lactulose. It is a better laxative. Advice 1. Syrup lactulose 2 teaspoonful per oral at bed time 2. Continue verapamil as suggested by your doctor 3. Take high fiber diet such as split peas, lentils, black beans, lima beans, baked beans, whole grains, vegetables such as artichoke, green peas, and sprouts and fruits 4. Drink 4 – 5 liters of water daily 5. Avoid straining while defecating 6. Regularly go to toilet. Never avoid if you feel pressure 7. Avoid excess intake tea and coffee after meal if tea and coffee contain tannins which cause constipation Thanks