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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Are Cramps Common During Spironolactone Intake?

I am taking spironolactone for high blood pressure and swelling of ankles. Now I am having leg cramps and spasms and also started getting cramping in my abdomen area (upper rib cage, right side around to my back). Should I be worried about this cramping, is this normal for this drug?
Thu, 3 Mar 2016
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General & Family Physician 's  Response
Hi & Welcome.
Thanks for posting your query on health care magic.
I can understand your concern.
Cramps seem to be due to the drug Spironolactone which causes hyperkalemia (increase potassium level in the blood) as one of its side effects. I would advise you to consult your treating doctor for an alternate but safer medication like Thiazide with or without Loop diuretic (like Furosemide) to treat both the hypertension and swollen ankles. These 'water pills' do not cause hyperkalemia and hence are safe and effectiv.e
Hope this answers your query.
A feed back is appreciated.
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Are Cramps Common During Spironolactone Intake?

Hi & Welcome. Thanks for posting your query on health care magic. I can understand your concern. Cramps seem to be due to the drug Spironolactone which causes hyperkalemia (increase potassium level in the blood) as one of its side effects. I would advise you to consult your treating doctor for an alternate but safer medication like Thiazide with or without Loop diuretic (like Furosemide) to treat both the hypertension and swollen ankles. These water pills do not cause hyperkalemia and hence are safe and effectiv.e Hope this answers your query. A feed back is appreciated.