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What Is The Standard Treatment Protocol For Systemic Candida Infection?

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Posted on Mon, 28 Jul 2014
Question: My daughter has been diagnosed with systemic (in the blood) candida infection. She has begun treatment with Nystatin. I have read that Nystatin is not indicated for systemic fungal infections. Is there a standard treatment protocol for systemic candida infection?
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Answered by Dr. Roopa Hiremath (1 hour later)
Brief Answer:
Amphotericin drug of choice

Detailed Answer:
Hi,

Thanks for choosing health care magic for your query.

I understand your concern about effective treatment for your daughter's disease.

Candida is a yeast like fungi and most cases of systemic candidiasis follow an endogenous infection by this commensal.

You are right that nystatin is more effective against candidial infections of the skin rather than systemic candidiasis.

Intravenous Amphotericin B, alone or in combination with Flucytosine, is recommended for systemic candidiasis.

Fluconazole can also be used effectively.

Antifungal suspceptibility testing can be done to determine the most effective antifungal in your daughter's case.

I hope I have cleared your doubts.

Please let me know, if I can assist you further.

Thanks.

Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Roopa Hiremath

Infectious Diseases Specialist

Practicing since :2002

Answered : 877 Questions

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What Is The Standard Treatment Protocol For Systemic Candida Infection?

Brief Answer: Amphotericin drug of choice Detailed Answer: Hi, Thanks for choosing health care magic for your query. I understand your concern about effective treatment for your daughter's disease. Candida is a yeast like fungi and most cases of systemic candidiasis follow an endogenous infection by this commensal. You are right that nystatin is more effective against candidial infections of the skin rather than systemic candidiasis. Intravenous Amphotericin B, alone or in combination with Flucytosine, is recommended for systemic candidiasis. Fluconazole can also be used effectively. Antifungal suspceptibility testing can be done to determine the most effective antifungal in your daughter's case. I hope I have cleared your doubts. Please let me know, if I can assist you further. Thanks.