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What Is The Cause And Treatment For Azoospermia?

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Posted on Fri, 7 Nov 2014
Question: I was directed by my doctor to carry out Doppler test to ascertain the cause of my Azoospermia. Though I had done other test in the past because I cannot father a child. But after which the test result showed my left varicocele is malfunctioning. And I cannot find any sign of such on my penis as I don't have any swollen vein or any kind of pain on my penis. I must add that there was a time I had untreated gonorrhea which resulted to staphylococcus which I think could be the cause of the Azoospermia. Please is there any drug you could recommend for me to enable sperm production. I need to have my own children but it is not possible now. The doctor said I should carrryout operation on my testis to correct the varicocele problem but I don't want to carryout any operation. Is there a non surgical way to correct this problem? Please your professional advice is highly sorted for. I am 40years and more than 6ft tall. HCM83374
Is there any drug that you can recommend for me that can permanently cure this staphylococcus as it goes and resurfaces gain? So many times I have treated it and it went and later came back. Please kindly help me as this is making me not to enjoy my marriage. Please note that I have strong erection and normal ejaculation. The only issue I have is zero sperm.
doctor
Answered by Dr. Rahul Tawde (4 hours later)
Brief Answer:
Surgical management and c/s guided antibiotic

Detailed Answer:
Hi
Thanks for posting the concern in the HCM.

After going through your history, my understanding is you have two issues-
1. Varicocele
2. Long standing uro-genital / only genital infection.

Both of these are well known impeding factors for spermatogenesis and viability of the sperms.
My experience is correction of varicocoele improves spermatogenesis. Researchers also opine that the correction can increase sperm retrieval rate. Now, let's find out what varicocele is.
It is abnormal ballooning of the venous network that drains blood from your testis. This is associated with abnormality in testicular blood flow. Now, their will be increased temperature alongwith accumulation of gonadotoxic metabolites locally. This alongwith adrenal hormone reflux, antisperm antibody formation etc. mechanisms kill your sperms even before they are fully mature.
Now this an anatomical defect, like presence of a lump on your forehead or presence of an extra finger. Have you ever heard that the latter conditions are cured by medications and not surgery? I haven't. So, The answer of the question whether there is a non-surgical way is NO.

Look, you don't have a chance to have a child from your own sperm now. So, you don't have to risk even 1% of your fertility. Rather, there is chance that after surgery the semen quality improves and you become able to be a proud father.

But, I won't persuade you for surgery. That is the choice which you have to make. Every surgery has its own risks, so has varicocelectomy. It is not a very complex surgery, but should be done by experienced hands.

Now, regarding the infection, I haven't read anywhere that gonorrhoea caused Staph infection. There may be the former, caused by gonococci and there may also be the latter, caused by the staphylococci. Both can be resistant to certain antibiotics. In co-infection they are often difficult to treat. So, what should we do?

The plan, get a confirmatory pin point diagnosis first, i.e infection of such and such site caused by such organism. Several tests are needed, including CBC, CRP, urea, creatinine, electrolytes, Urine RE, C/S, urethral swab C/S and ultrasound examination of lower abdomen. After getting the exact diagnosis and antibiotic sensitivity report, proper antimicrobial medication at proper dosage, interval and duration would be able to cure you.

For that you need to consult a Venereal disease specialist. Also take your partner with you because she may need evaluation.

If you are satisfied with the above answer, please close the thread and rate it.
Regards,
Dr. Kaushik Sarkar
Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
Dr.
Dr. Rahul Tawde

General & Family Physician

Practicing since :1980

Answered : 1 Question

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What Is The Cause And Treatment For Azoospermia?

Brief Answer: Surgical management and c/s guided antibiotic Detailed Answer: Hi Thanks for posting the concern in the HCM. After going through your history, my understanding is you have two issues- 1. Varicocele 2. Long standing uro-genital / only genital infection. Both of these are well known impeding factors for spermatogenesis and viability of the sperms. My experience is correction of varicocoele improves spermatogenesis. Researchers also opine that the correction can increase sperm retrieval rate. Now, let's find out what varicocele is. It is abnormal ballooning of the venous network that drains blood from your testis. This is associated with abnormality in testicular blood flow. Now, their will be increased temperature alongwith accumulation of gonadotoxic metabolites locally. This alongwith adrenal hormone reflux, antisperm antibody formation etc. mechanisms kill your sperms even before they are fully mature. Now this an anatomical defect, like presence of a lump on your forehead or presence of an extra finger. Have you ever heard that the latter conditions are cured by medications and not surgery? I haven't. So, The answer of the question whether there is a non-surgical way is NO. Look, you don't have a chance to have a child from your own sperm now. So, you don't have to risk even 1% of your fertility. Rather, there is chance that after surgery the semen quality improves and you become able to be a proud father. But, I won't persuade you for surgery. That is the choice which you have to make. Every surgery has its own risks, so has varicocelectomy. It is not a very complex surgery, but should be done by experienced hands. Now, regarding the infection, I haven't read anywhere that gonorrhoea caused Staph infection. There may be the former, caused by gonococci and there may also be the latter, caused by the staphylococci. Both can be resistant to certain antibiotics. In co-infection they are often difficult to treat. So, what should we do? The plan, get a confirmatory pin point diagnosis first, i.e infection of such and such site caused by such organism. Several tests are needed, including CBC, CRP, urea, creatinine, electrolytes, Urine RE, C/S, urethral swab C/S and ultrasound examination of lower abdomen. After getting the exact diagnosis and antibiotic sensitivity report, proper antimicrobial medication at proper dosage, interval and duration would be able to cure you. For that you need to consult a Venereal disease specialist. Also take your partner with you because she may need evaluation. If you are satisfied with the above answer, please close the thread and rate it. Regards, Dr. Kaushik Sarkar