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What Does The Following PET Scan Report Indicate?

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Posted on Wed, 19 Nov 2014
Question: Part of pet scan report says
16 mm focus of intense tracer uptake peripherally in seg 6 with SUV XXXXXXX of 5.2.

Appearances are suspicious of peripheral seg 6 liver metastases and consistent with a aortocaval nodal met.

So there is 1 liver met right and 1 node?

Is the uptake high at 5.2?
doctor
Answered by Dr. Prasanna Heijebu (2 hours later)
Brief Answer:
2 metastatic foci on your pet scan

Detailed Answer:
Hello Sir,

I understood your query and concern.

You are absolutely right.
There is one metastatic focus in segment 6 of liver and one metastatic lymph node in aortico-caval region.

Yes your suv is high.
SUV greater than 3 is considered high.

Hope I have answered your query at the moment.
Post your further queries,if any.
Thank you.
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Prasanna Heijebu (1 hour later)
What would be best treatment for this bearing in mind there is 1 liver met .

Hiwever I am
Confussed that cea in sept was 9.8. Then chemo was stopped at 4 th cycle as scans were being done and a recent cea of yesterday has dropped to 6 . Why might that be ?

My dad has not have chemo for about 8 weeks now
doctor
Answered by Dr. Prasanna Heijebu (2 hours later)
Brief Answer:
Chemoembolisation is most employed.

Detailed Answer:
Hello,

welcome again.

Cea is a tumour marker.Its not an accurate tool for detecting the metastasis.

Hence do not rely on these and get confused.

The treatment for solitary metastatic deposit in liver has wide treatment options like
1.chemoembolisation
2.location resection
3.alcohol injection.

The overall outcome of this solitary metastasis is good.

Post your further queries, if any.
Thank you

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
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Follow up: Dr. Prasanna Heijebu (1 hour later)
What about the aortocaval node?
doctor
Answered by Dr. Prasanna Heijebu (5 minutes later)
Brief Answer:
Lymph node draining liver.

Detailed Answer:
Hello,

Aortocaval node is draining lymph node from the liver which is located in the region of abdominal aorta and inferior vena cava,which are 2 large blood carrying vessels in the abdominal cavity.

These lymph nodes are frequently involved in cancers.

Thank you.
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Prasanna Heijebu (15 minutes later)
Can anything be done re this node ? And would chemo first be best option ?
doctor
Answered by Dr. Prasanna Heijebu (34 minutes later)
Brief Answer:
Chemoradiation+/-surgical resection

Detailed Answer:
Hi,

A single involved node can be precisely resected.

Chemotherapy would also be sill be a better option.

But one has to expect high risk of recurrence, if occult metastasis is present in the nearby draining lymph nodal stations.
Single node involvement has overall good results.

Thank you.
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Prasanna Heijebu (2 hours later)
Is that way they wAnt to do chemo first due to 1 node involved to try target the microscopic cells ?

Is this serious with 1 liver met and 1 node ?
doctor
Answered by Dr. Prasanna Heijebu (3 hours later)
Brief Answer:
Tumour shrinkage is the principle.

Detailed Answer:
Hello XXXXXXX

Its always a serious issue when lymph nodal metastasis has occurred.

This state always represents a widely spread disease, especially in liver cancers.
But since the pet scan in your case is showing only solitary lymph nodal involvement, it leaves some hope for doctors to attack and destroy it, before it spreads to other lymph nodes and organs.

This is sometimes called sentinel node surveillance.
Sentinal implies first draining lymph node involved.
When appropriately treated, a cancer can be largely controlled at this stage.

But the success is usually in the range of 30-50% in case of liver mets, but still the doctors try to exploit this survival advantage.

Hence in most cases, chemo+/-radiation is offered to shrink the met deposits completely in the node before proceeding to surgery to reduce the risk of tumour spillage while operating.


Post your further queries, if any.
Thank you.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Prasanna Heijebu (10 hours later)
The thing is 2 lesions were found . Both 16 mm but only 1 had a uptake of 5.2. The other did not have an uptake .

Could the other lesion have been a met that has now been killed with the xeloda ? Both were new findings
doctor
Answered by Dr. Prasanna Heijebu (9 hours later)
Brief Answer:
Yes its a liver met.

Detailed Answer:
Hi XXXXXXX

Yes you are right,

the one which did not have the uptake is likely to have been cured by xeloda.

Yes most probably the other lesion could have been a liver met.

Thank you.


Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
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Follow up: Dr. Prasanna Heijebu (3 hours later)
Why might the xeloda
Not have done anything to the 1 liver met and node then ?

He had 4 cycle so far
doctor
Answered by Dr. Prasanna Heijebu (16 minutes later)
Brief Answer:
Response varied to intrinsic genetic defects.

Detailed Answer:
Hi XXXXXXX

The response of mets in liver cancer to chemotherapy vary widely.

This is due to the intrinsic behaviour of mets due to acquired DNA changes/mutaions.

Hence all mets do not respond the same as time passes on due to the intrinsic progressive genetic defects in hepatocellular carcinoma.

Thank you.
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Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
doctor
Answered by
Dr.
Dr. Prasanna Heijebu

General & Family Physician

Practicing since :2010

Answered : 1422 Questions

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What Does The Following PET Scan Report Indicate?

Brief Answer: 2 metastatic foci on your pet scan Detailed Answer: Hello Sir, I understood your query and concern. You are absolutely right. There is one metastatic focus in segment 6 of liver and one metastatic lymph node in aortico-caval region. Yes your suv is high. SUV greater than 3 is considered high. Hope I have answered your query at the moment. Post your further queries,if any. Thank you.