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What Does My Biopsy Test Result Indicate?

Posted on Fri, 1 Jul 2016

Question: Dear doctor
I m XXXXXXX one month before I have pain in my left hand 2nd metacarpal doctor suggest for x Ray and MRI. After that my orthopedist suggest that there is a cavity on 2nd metacarpal and remove through surgery and take biopsy.
After 4-5 day the biopsy report come.
In report there is a line that ZN stain for AFB is negative but doctor to told be that u have to take the medicine for TB. That is osteomyelitis TB
I read multiple article on Internet and regarding for AFB test.
Please suggest is I m really suffered with he diseases or not.

Answered by Dr. Dr. Naveen Kumar Sharma (1 hour later)

Brief Answer:
It is difficult to confirm TB

Detailed Answer:
Hello,
I have studied your case. TB is very common in our country but it is not possible to confirm the diagnosis.So doctors gives TB medication for one or two months and if disease is getting better then it is continued. In your case biopsy report is not positive for TB. I would like to see your MRI, X ray and Blood reports. I can help you in confirming if it is TB or not. But just on the basis of negative biopsy we can not conclude that you do not have TB.
Please send me your Mri, X ray and blood reports. I will try my best to help you.
Thanks.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Naveen Kumar Sharma (52 minutes later)

But doctor I have no symptom of TB and there are no swelling and inflammation in my hand.
The only cause is that there is pain on my 2 nd metacarpal. And it happened only when I press that specific point only.

All the reports are take back by DMCH Hospital for there record.
I have only pathology report.
Please help should I take second opinion from PGI or other big institute.
Thanks in advance

Answered by Dr. Dr. Naveen Kumar Sharma (9 hours later)

Brief Answer:
There is no specific symptoms of TB

Detailed Answer:
Hello,
TB is possible even if their is no swelling or inflammation. Other possibility is tumour. So If you do not have any report then you need to get a repeat MRI and biopsy. You can take opinion from PGI. There are only two options.
1.do not take any treatment and get x rays every month to see if disease is progressing or not.
2.get Anti TB medication and see if they are responding or not.
I would prefer second option.
Thanks

Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar