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What Does Inability To Conceive Despite Taking Siphene Suggest?

Posted on Fri, 19 Jun 2015

Question: started planning in XXXXXXX 2015 and had a chemical pregnancy in tat month..so from April 2015 took siphene 50 mg from 6th -11th day of cycle...in May siphene 50 mg again but from 2nd - 6th day of cycle...and for both months taking dupaston 10mg from 15th -25th day..in both months i didnt conceived ..and also in both months opk was positive for 3-4 days...then negative ..is it normal tat lh surge stays for 3-4 days???is this reason with tablet also i didnt conceive??
Now doc has increased the dose of siphene from 50 to 100..is there any harm to go for such treatment so early ..

Answered by Dr. Dr. Rakhi Tayal (32 minutes later)

Brief Answer:
Can try with higher dose.

Detailed Answer:
Hello,
Thanks for trusting us with your health concern.
It is normal for the LH surge to remain positive for 3-4 days. You need to consider it as positive only when the test line is darker than the control line. If the test line remains darker than control line for 3-4 days continuously then PCOD needs to be ruled out. You should wait for at least 3 days after finishing Clomid to start testing for LH surge. Clomid can cause a false positive result.
Since you have not conceived with 50mg dose the increased dosage can be tried. Ovulation study by serial ultrasound scans will also help.
Please feel free to discuss further. I will be glad to answer the follow up queries that you have.
Wishing you good health.
Regards.
Dr. Rakhi Tayal.
For future query, you can directly approach me through my profile URL http://bit.ly/Dr-Rakhi-Tayal

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Rakhi Tayal (6 minutes later)

before taking siphene 50 mg...i used to get opk positive for one day ..my query is tat only..after taking siphene 50 mg ..m getting 3-4 days dark opk..test line looks equally dark as control line...then it will turn negative...so does tablets are affecting this lh surge..as doc has put me on 100 mg now..so m worried...

Answered by Dr. Dr. Rakhi Tayal (1 hour later)

Brief Answer:
Yes it can affect LH surge.

Detailed Answer:
Hello.
Thanks for writing again.
Clomiphene can affect the LH surge. Increasing the dose is necessary as there has been no response with 50 mg dose.
Hope my answer is helpful.
Do accept my answer in case there are no further queries.
Regards.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr. Rakhi Tayal (9 minutes later)

Thanks for ur answer..but as u mention PCOD related to lh surge..and as siphene dose is increasing from 50mg to 100mg...will it not affect my health..like any sideaffects..as it is increasing my lh surge..bcoz of this should i worry about PCOD because of siphene tablets(side affect)

Answered by Dr. Dr. Rakhi Tayal (13 minutes later)

Brief Answer:
Well tolerated. Minor side effects only.

Detailed Answer:
100mg of siphene is a normal dose. It is not a very high dose. It is well tolerated. Can cause a mild increase in bleeding during periods and a vaginal dryness as a side effect.
Regards.

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar