HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

What Causes Severe Cold, Diarrhea And Itching In Hands And Feet While On Flexeril?

default
Posted on Thu, 16 Jun 2016
Question: Two weeks ago, came down with cold. Took flexeril for unrelated back injury. Woke up next morning with itching hands and feet, hypersensitive, and over a couple days, after recommendation for aleve by my doc, hsving gray ish diahrea. Also XXXXXXX urine. Took prednisone to stop allergic reacfion, made thjngs worse. Presented to ER, all tests negative except increased liver count (see below, lower bilirubin one is from hospital release). After 18 hours on fluids, diahrea and urine color clear up, no pain, slight soreness on right side, fatigue, bad itching, jaundice continue, but urine and stool are back to normal. Any thoughts? Blockage?
doctor
Answered by Dr. Dr. Klerida Shehu (1 hour later)
Brief Answer:
Please follow...

Detailed Answer:
Hi and welcome to HCM!
I am Dr.Klerida Shehu gastroenterologist and I ma glad to assist you.

I read carefully all your concerns and I can sa y as follows:
1. I need to know more about your medical data like:
- do you have done hepatitis tests A,B,C ?
- dose abdominal ultrasound shows about a biliary tree blockage ?
- Is GGT level normal or you haven't done it?
2. Your symptoms may be related with :
- toxic hepatitis after Flexeril use
- viral liver infection like virus A, B , C or cytomegalovirus or EBV.
- since alkaline phosphatase is hight too than biliary tree blocage should be ruked out with MRCP.
It would be great if you can upload to me your other medical data, so I can check them by myself.
Hope it was helpful to you!
Dr.Klerida
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Dr. Klerida Shehu (21 minutes later)
1. Tested negative for hep and all autoimmune disorders. GGT was not done. CT scan was done, not ultrasound, and no abormality was found in pancreas, billiary tree, etc. so im assuming thats why i didnt do that scan.

2. Ive noticed slow, steady inprovement over last couple days. Energy levels up a bit.Should also note that my parents and i all suffer from gilberts syndrome. Could this be related to that?

doctor
Answered by Dr. Dr. Klerida Shehu (18 hours later)
Brief Answer:
Please follow..

Detailed Answer:
Hi back,
With regards to XXXXXXX syndrome your test results are not related with it.
XXXXXXX syndrome is not associated with high transaminase level and high alkaline phosphatase level.
Since you have done ct scan and it was normal than there is no biliary blackage.
At your situation to my opinion your symptoms seems to be related with toxic hepatitis due to recently drug usage.
Otherwise I suggest to do GGT level since direct bilirubin is increased.

Hope it was helpful to you.
Dr.Klerida
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Dr. Klerida Shehu (2 hours later)
In regards to the toxic hepatitis, theres essentially not much treatment, other than ceasing the medication and allowing your body to heal, right?
doctor
Answered by Dr. Dr. Klerida Shehu (12 hours later)
Brief Answer:
Please follow

Detailed Answer:
Hi back,
In cases like severe toxic hepatitis is used contisosteroid treatment for at least 4 weeks.
In other cases like your were it is not related with too high level of transaminases than I don't recommend corticosteroids.
In such cases like your I prefer to use only vitamin therapy ( vitE and B group)and liquids.
Hope it was helpful to you!
Dr.Klerida
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
default
Follow up: Dr. Dr. Klerida Shehu (3 hours later)
And what is the range of recovery time for a healthy 31 yo non drinker no smoker?
doctor
Answered by Dr. Dr. Klerida Shehu (18 hours later)
Brief Answer:
Please follow. .

Detailed Answer:
Hi back,
Usually the recovery time in healthy patient and a moderate form like in your case , needs 10-12 weeks .
During this time the transaminases return in normal level.
Wish you health.
Dr.Klerida
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Dr. Klerida Shehu

Gastroenterologist

Practicing since :2006

Answered : 2266 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
What Causes Severe Cold, Diarrhea And Itching In Hands And Feet While On Flexeril?

Brief Answer: Please follow... Detailed Answer: Hi and welcome to HCM! I am Dr.Klerida Shehu gastroenterologist and I ma glad to assist you. I read carefully all your concerns and I can sa y as follows: 1. I need to know more about your medical data like: - do you have done hepatitis tests A,B,C ? - dose abdominal ultrasound shows about a biliary tree blockage ? - Is GGT level normal or you haven't done it? 2. Your symptoms may be related with : - toxic hepatitis after Flexeril use - viral liver infection like virus A, B , C or cytomegalovirus or EBV. - since alkaline phosphatase is hight too than biliary tree blocage should be ruked out with MRCP. It would be great if you can upload to me your other medical data, so I can check them by myself. Hope it was helpful to you! Dr.Klerida