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What causes numbness, tingling and twitching in legs?

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Posted on Mon, 3 Aug 2015
Question: I have had tingling and twitching in my legs for approx 3 years (on and off). Some numbness. The tingling and twitching go away upon standing. Not painful. I have had complete blood workup, thyroid, comprehensive, cell/dyn and B-12. Everything normal. Had the EMG test (needle in muscle and electric shocks) everything normal. Am 55 years old, female, peri-menopausal, with mild arthritis in hips. Was a runner for 30 plus yrs until recently. Some pain in left hip, exercise dependent.
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Answered by Dr. Neeraj Kumar (20 minutes later)
Brief Answer:
Possibility of neuropathy or benign fasciculation syndrome

Detailed Answer:
Hello dear,
I have gone through your question and understand your concerns.
Your symptoms are Intermittent with no significant progression. If no motor weakness, wasting of muscle, thining of limbs is present and only muscle twitching is present then it may be benign fasciculation syndrome.
No back pain with tingling in both lower limbs may also be present in small fiber neuropathy which is usually not picked on nerve conduction studies.
You can get immune electrophoresis for myeloma.
I hope other routine investigation for vitamin B12, vitamin D3, blood sugar, urea, creatinine, liver function test and Ana has been done and normal.
If nothing come positive then you can try amitryptiline or pregabalin with calcium and vitamin D 3 supplements.
You can consult a neurologist who can examine you properly and advice accordingly.
Hope you found the answer helpful.
Please provide more information.
Do get back to me for further queries.
Regards
Dr Neeraj Kumar
Neurologist
Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Follow up: Dr. Neeraj Kumar (53 minutes later)
Yes, all above tests have been done and are normal.
doctor
Answered by Dr. Neeraj Kumar (34 minutes later)
Brief Answer:
Try below medication for few months

Detailed Answer:
Hello dear,
Then try amitryptiline or nortryptiline plus pregabalin and calcium with vitamin D3.
It's not serious according to present scenario.
If you don't have significant improvement and symptoms persists or progress you can consult a good neurologist near your residence or visit a neuro centre in apex government centre of your state.
Hope you found the answer helpful.
Regards
Dr Neeraj Kumar
Neurologist
Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Dr. Neeraj Kumar

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Practicing since :2006

Answered : 2263 Questions

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What causes numbness, tingling and twitching in legs?

Brief Answer: Possibility of neuropathy or benign fasciculation syndrome Detailed Answer: Hello dear, I have gone through your question and understand your concerns. Your symptoms are Intermittent with no significant progression. If no motor weakness, wasting of muscle, thining of limbs is present and only muscle twitching is present then it may be benign fasciculation syndrome. No back pain with tingling in both lower limbs may also be present in small fiber neuropathy which is usually not picked on nerve conduction studies. You can get immune electrophoresis for myeloma. I hope other routine investigation for vitamin B12, vitamin D3, blood sugar, urea, creatinine, liver function test and Ana has been done and normal. If nothing come positive then you can try amitryptiline or pregabalin with calcium and vitamin D 3 supplements. You can consult a neurologist who can examine you properly and advice accordingly. Hope you found the answer helpful. Please provide more information. Do get back to me for further queries. Regards Dr Neeraj Kumar Neurologist