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What causes false positive results for THC while on Lisinopril and Nitrostat?

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Posted on Mon, 22 Jun 2015
Question: i am taking several medications. i want to know if any of these can cause a false positive for a thc drug test. I just went to probation and have absolutely not been smoking any marijuiannas. here is the med list. please advise. lisinopril, labetalse, brilinta,nitrostat, ato?vastain. Please, please, please advise. is there even a small possibility that these drugs or the combination there of could have triggered a false positive?
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Answered by Dr. Matt Wachsman (2 hours later)
Brief Answer:
a very good question deserving a very good answer

Detailed Answer:
which would ultimately be ... you cannot know.
The local labs offer over a dozen different urine screens. They vary from sticking to a piece of cardboard with antibodies on it that you can get for 20 bucks at the pharmacy... to quantitative measurement with Gas chromatography-mass spectroscopy with validation. The cardboard can stick to anything and give a false positive and it doesn't matter what you are taking. THe GC-MS is very reliable and also doesn't matter what you are taking.
BUT
there are some drugs that look similar to drugs of abuse and are Well-Known to cause trouble.
http://www.aafp.org/afp/2010/0301/p635.html
this is a general discussion of the topic and quite readable.
Anything like a stress hormone might possibly look like amphetamine. That includes the labetalal. Nitrostat is metabolized so fast that unless they are doing very very careful looks for XXXXXXX nitrate .. which is almost the same chemical... it won't come up.
ww.ncbi.nlm.nih.gov/pubmed/0000
basically, other than labetalol, the others do not look to be a problem BUT there is a few percent chance of a false positive EVEN WIHTOUT THE MEDS
That's about it. That includes looking over a few score of titles, searching the medline and my own previous inquiries into the subject. It's doubtful you're going to find more info beyond this.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Dr. Matt Wachsman

Addiction Medicine Specialist

Practicing since :1985

Answered : 3703 Questions

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What causes false positive results for THC while on Lisinopril and Nitrostat?

Brief Answer: a very good question deserving a very good answer Detailed Answer: which would ultimately be ... you cannot know. The local labs offer over a dozen different urine screens. They vary from sticking to a piece of cardboard with antibodies on it that you can get for 20 bucks at the pharmacy... to quantitative measurement with Gas chromatography-mass spectroscopy with validation. The cardboard can stick to anything and give a false positive and it doesn't matter what you are taking. THe GC-MS is very reliable and also doesn't matter what you are taking. BUT there are some drugs that look similar to drugs of abuse and are Well-Known to cause trouble. http://www.aafp.org/afp/2010/0301/p635.html this is a general discussion of the topic and quite readable. Anything like a stress hormone might possibly look like amphetamine. That includes the labetalal. Nitrostat is metabolized so fast that unless they are doing very very careful looks for XXXXXXX nitrate .. which is almost the same chemical... it won't come up. ww.ncbi.nlm.nih.gov/pubmed/0000 basically, other than labetalol, the others do not look to be a problem BUT there is a few percent chance of a false positive EVEN WIHTOUT THE MEDS That's about it. That includes looking over a few score of titles, searching the medline and my own previous inquiries into the subject. It's doubtful you're going to find more info beyond this.